Saturday, September 20, 2008

drug origins

i'm constantly amazed where drugs come from. some are from plants, some are from animals, some are made in a labratory, some are found in nature and then modified in labratories.

this one has a pretty cool history

Ergotamine: this is a medicine used to abort migraines once they have started. it is a partial agonist at 5-HT (serotonin) receptors, causing vasoconstriciton and suppression of meningeal nociceptive pathways.

History: derived from a fungus called claviceps purpurea, which infects grain. People would eat this invected grain and have prolonged vasospasms, gangrene, paresthesias, and spontaneous aborthions. It was known as St. Anthony's fire, because for relief of the disease, people would pilgramage to St. Anthony's shrine. In reality, they would be healed from this because they were eating a fungus-free diet on their pilgramige.

Other drug derivations.

Opioids: Poppy seeds. This group includes morphine, codine, and heroin.
Atropine: an antimuscarinic drug used to decrease the parasympathetic nervous system. it is derived from the plant Atropa belladonna. This plant got its name because ectracts from the plant were used by Italian women to dilate their pupils, a very attractive trait (apparently). I know thats the first thing i look at when i see a beautiful woman... her pupil size. mmm... i love me some big pupils... big, bilateral, dilated pupils... ok, i better stop. im going to get in trouble for this one.

2 comments:

Unknown said...

Unless your inferior rectus muscles are completely paralyzed, that last statement is obviously not true.

Nice try, though.

jdawg97 said...

Wow i didnt no that some drugs come from animals. Can u list some pls?